Table 1.

Summary of patient demographic parameters.

Characteristic	Values
Total patients (n)	90
M/F	49/41
Age (years)	47 ± 15
Weight (kg)	82 ± 20
CBZ dose (mg/day)	763 ± 463
Half-life (h)	21.43 ± 12.19 (range: 7.76–114.72)
Clearance (l/h/kg)	42.64 ± 17.23 (range: 10.17–95.37)
CBZ-E:CBZ	0.15 ± 0.06 (range: 0.05–0.38)
CBZ-diol:CBZ-E	2.73 ± 0.88 (range: 0.84–5.89)
Race	Caucasians: 59 (F: 23 and M: 36) African–American: 31 (F: 18 and M: 13)

Except where indicated, values are presented as the mean ± standard deviation.

CBZ: Carbamazepine; CBZ-diol: Carbamazepine-10,11-trans dihydrodiol; CBZ-E: Carbamazepine 10-11 epoxide; F: Female; M: Male.