Figure 4.
Dose-dependent effect of the survivin-targeting molecules on cell proliferation and viability. Cells were treated with DMSO vehicle control (indicated as 0 µm), S12, S2 or S10 for 48 h at the indicated concentrations. The percentage of viable cells was evaluated by MTT assay. The error bars represent s.d. (a) AsPc1 cells; (b) HeLa cells; (c) SKBR3 cells; (d) DAOY cells and (e) HCT116 p53+/+ and HCT116 p53−/− cells treated with S12.
