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. 2012 Dec 10;5(2):561–566. doi: 10.3892/etm.2012.855

Figure 4.

Figure 4.

mRNA expression levels of RB, E2F1 and HPV-E7 in HeLa cells following treatment with BAK and NK cells. (A) HPV-E7 mRNA expression was very similar among BAK, NK and control groups. (B) RB mRNA expression by HeLa cells increased following treatment with BAK or NK cells, but no significant difference was observed between the two groups (P>0.05). (C) E2F1 mRNA expression decreased almost 3-fold after treatment with BAK or NK cells, but there was also no significant difference between the BAK and NK groups (P>0.05).*P<0.05, compared with the blank control. RB, retinoblastoma; HPV, human papillomavirus; BAK, BCG-activated killer; NK, natural killer; BCG, Bacillus Calmette-Guerin.