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MSC paracrine signaling induces an increase in ICa,L. (A) Representative confocal line scan images and F/F0 plots from a cardiomyocyte in control conditions (Ctrl) and (B) during superfusion with CPA. (C) Representation of the mean Ca transient amplitude in Ctrl (black) and CoC (white) conditions in the presence of CPA. (D) Current voltage relationship of ICa,L measured by whole cell voltage clamp in Ctrl (●, n=12) and ConT treated (3h; o, n=11) VMs (*=p<0.05).
