Table II.

Morphological changes in rat femur sections.

Group	BM cells	Fat cells	Fibrosis	Sclerosis	Reticulin fibers
1	++	+	0	0	0
2	+	++	+++	+++	+++
3	+++	+	0	0	0
4	+++	+	0	0	0
5	+++	+	++	+	++
6	+++	+	+	+	++
7	+++	+	++	+	++
8	+++	+	+	+	++

Changes are scored 0, +, ++ and +++, in increasing order of severity. Group 1, control; Group 2, lead alone; Group 3, Carica papaya alone (50 mg/kg); Group 4, Carica papaya alone (200 mg/kg); Group 5, lead and post-treatment with Carica papaya (50mg/kg); Group 6, lead and post-treatment with Carica papaya (200 mg/kg); Group 7, pre-treatment with Carica papaya (50 mg/kg) followed by lead; Group 8, pre-treatment with Carica papaya (200 mg/kg) followed by lead; BM, bone marrow.