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. 2012 Jul 17;206(10):1577–1588. doi: 10.1093/infdis/jis395

Figure 3.

Figure 3.

Tissue histology following nanoformulated antiretroviral therapy (nanoART) injections in mice. A, Hematoxylin and eosin staining of sections from liver, spleen, lung, and kidney in nonreconstituted, noninfected NSG mice treated with 2 weekly subcutaneous injections of 250 mg/kg each atazanavir (ATV)/ritonavir (RTV) (M3001 + M2001). B, Tissue histology of peripheral blood lymphocyte (PBL)–reconstituted, human immunodeficiency virus type 1 (HIV-1)–infected NSG mice treated with 2 weekly subcutaneous injections of either ATV/RTV (H3001 and H2001, 250 mg/kg each) or ATV/RTV/efavirenz (EFV) (H3001, H2001, and H4001, 100 mg/kg each) or untreated (PBS). All images at ×200 magnification. Bar = 100 μm.