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. 2012 Nov 13;5(2):572–580. doi: 10.3892/etm.2012.809

Figure 2.

Figure 2.

Structural and functional domains of the glucocorticoid receptor (GCR). The structural domains of the GCR: A/B, C, D, E and F determine the biological functions of the functional domains: activation function 1 (AF1), DNA-binding domain (DBD), nuclear localization sequence (NLS), ligand-binding domain (LBD) and AF2. Detailed description and relevant literature in the text. Authors’ own elaboration based on (4,8,9,15).