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Comparative analysis of NR3C1 gene Tth111I polymorphism frequency in healthy controls vs. patients with asthma characterized by a control profile corresponding to an ACT™ score ≥20.
| Healthy controls n (expected) | Asthma ACT™ score ≥20 n (expected) | OR | CI | Chi2 | P-value | |
|---|---|---|---|---|---|---|
| GG | 64 (81.04) | 33 (31.84) | ||||
| AG | 136 (101.92) | 44 (46.32) | ||||
| AA | 15 (32.04) | 18 (16.84) | ||||
| [AG] vs. [GG] | 0.270 | 0.125–0.579 | 12.25 | 0.00047 | ||
| [AA] vs. [GG] | 0.430 | 0.192–0.960 | 4.35 | 0.03699 | ||
| [AA] vs. [AG + GG] | 0.321 | 0.154–0.668 | 9.93 | 0.00163 |
