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Comparative analysis of NR3C1 gene Tth111I polymorphism frequency in healthy controls vs. patients with severe non-allergic asthma characterized by control profile corresponding to ACT™ score ≥20.
| Healthy controls n (expected) | Severe non-allergic asthma ACT™ score ≥20 n (expected) | OR | CI | Chi2 | P-value | |
|---|---|---|---|---|---|---|
| GG | 64 (81.04) | 4 (2.25) | ||||
| AG | 136 (101.92) | 1 (4.50) | ||||
| AA | 15 (32.04) | 4 (2.25) | ||||
| [AG] vs. [GG] | 0.028 | 0.003–0.263 | 22.21 | 2.440e-06 | ||
| [AA] vs. [AA + GG] | 0.094 | 0.023–0.386 | 15.62 | 0.00008 |
