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Comparative analysis of NR3C1 gene Tth111I polymorphism frequency in healthy controls vs. patients with severe allergic asthma characterized by a control profile corresponding to an ACT™ score ≥20.
| Healthy controls n (expected) | Severe allergic asthma ACT™ score ≥20 n (expected) | OR | CI | Chi2 | P-value | |
|---|---|---|---|---|---|---|
| GG | 64 (81.04) | 4 (3.52) | ||||
| AG | 136 (101.92) | 5 (5.96) | ||||
| AA | 15 (32.04) | 3 (2.52) | ||||
| [AG] vs. [GG] | 0.184 | 0.040–0.847 | 5.75 | 0.01648 | ||
| [AA] vs. [AG + GG] | 0.225 | 0.055–0.920 | 5.06 | 0.02453 |
