Table 3.
Difference in expected survival (in months) between interventions as obtained with random effects network meta-analysis model with and without treatment-by-covariate interaction
| |
Random effects model without covariate interaction (model 1) |
Random effects model with treatment specific covariate interaction (model 2) |
Random effects model with constant treatment-by-covariate interaction (model 3) |
|||
|---|---|---|---|---|---|---|
| Median of posterior distribution | 95% Credible Interval | Median of posterior distribution | 95% Credible Interval | Median of posterior distribution | 95% Credible Interval | |
| DTIC + IFN vs. DTIC |
−1.12 |
(−4.20; 3.49) |
−2.46 |
(−5.72; 1.91) |
−1.90 |
(−5.10; 2.22) |
| DTIC + non-IFN vs. DTIC |
3.63 |
(−1.72; 10.75) |
3.77 |
(−1.04; 10.72) |
3.21 |
(−2.39; 9.65) |
| non-DTIC vs. DTIC |
2.66 |
(−2.38; 13.49) |
1.16 |
(−7.51; 25.76) |
6.60 |
(−0.78; 21.39) |
| DTIC + non-IFN vs. DTIC + IFN |
4.71 |
(−1.38; 11.37) |
6.26 |
(0.26; 13.29) |
5.13 |
(−1.15; 11.50) |
| non-DTIC vs. DTIC + IFN |
3.81 |
(−2.40; 14.11) |
3.46 |
(−6.00; 27.88) |
8.48 |
(−0.65; 24.00) |
| non-DTIC vs. DTIC + non-IFN | −0.84 | (−9.15; 10.3) | −2.79 | (−13.90; 22.17) | 3.27 | (−6.72; 20.74) |