Table 3.
Impact of patients’ characteristics and comorbidities on adherence and persistence to UC treatments
| |
Adherence |
Persistence |
||
|---|---|---|---|---|
| Patient’s adherent over 12 months n (%) | Adjusted OR [95% CI] | Patient’s persistent at 12 months n (%) | Adjusted OR [95% CI] | |
| Sex |
|
|
|
|
| · Male |
222 (30.5) |
1.3 |
365 (50.1) |
1.4 |
| · Female |
243 (25.5) |
[1.05–1.6] |
400 (42.0) |
[1.1–1.7] |
| Age |
|
|
|
|
| · < 60 |
201 (23.3) |
1.6 |
381 (44.1) |
NS |
| · ≥ 60 |
264 (32.3) |
[1.3–2.0] |
384 (49.9) |
|
| Previous use of corticosteroids |
|
|
|
|
| · Yes |
142 (28.2) |
NS |
231 (45.8) |
NS |
| · No |
323 (27.4) |
|
534 (45.4) |
|
| Concurrent use of corticosteroids |
|
|
|
|
| · Yes |
179 (32.7) |
1.4 |
273 (49.8) |
1.4 |
| · No |
286 (25.2) |
[1.1–1.8] |
492 (43.4) |
[1.1–1.7] |
| Heart disease |
|
|
|
|
| · Yes |
210 (30.2) |
NS |
321 (46.2) |
NS |
| · No |
255 (25.9) |
|
444 (45.0) |
|
| Respiratory illness |
|
|
|
|
| · Yes |
153 (26.8) |
NS |
247 (43.3) |
1.2 |
| · No |
312 (28.1) |
|
518 (46.6) |
[1.004–1.548] |
| Hypertension |
|
|
|
|
| · Yes |
262 (31.1) |
NS |
403 (47.9) |
1.2 |
| · No |
203 (24.2) |
|
362 (43.1) |
[1.01–1.50] |
| Diabetes |
|
|
|
|
| · Yes |
167 (30.4) |
NS |
515 (45.5) |
NS |
| · No |
298 (26.3) |
|
250 (45.5) |
|
| Chronic disease score |
|
|
|
|
| · Yes |
159 (23.2) |
NS |
296 (43.3) |
NS |
| · No | 306 (30.7) | 469 (47.0) | ||
CI, confidence interval; NS, not significant; OR, odds ratio; UC, ulcerative colitis.