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CPH inhibit the CD2-induced interaction of cofilin with the actin cytoskeleton in vivo. PBT were incubated without (None) or with 0.5, 2, or 5 μM peptides M plus W (M/W) or peptide Q (Q) and stimulated via CD2. Actin and cofilin in actin cytoskeletal fractions were detected by immunoblotting. This experiment was performed three times with comparable results.
