Fig. 2.

CPH inhibit CD2-induced T cell proliferation without affecting cell viability. (A) PBT were incubated with peptides M/W or Q or without peptides (None) and stimulated via CD2 (CD2) or left unstimulated (RT). After 48 h, cell proliferation was quantified by [³H]thymidine incorporation. Proliferation of CD2-stimulated cells without CPH was taken as 1 (means ± SE of four independent experiments). (B) PBT were pretreated and stimulated as in A. After 72 h, cell viability was assessed through propidium iodide exclusion (means ± SE of three independent experiments).