Fig. 7.

CPH inhibit antigen-induced intracellular IFN-γ production. T cells were preincubated without (None) or with peptides M/W. Stimulations were performed with sheep erythrocyte rosetting-negative peripheral blood mononuclear cells as APCs loaded with SEB, control antigen (Control Ag), or CMV antigen (CMV Ag) or without antigen (No Ag). The frequency of antigen-reactive CD4⁺ T cells is given as the percentage of IFN-γ⁺ cells [including mean fluorescence index (MFI) of IFN-γ⁺ cells]. This experiment was performed three times with comparable results.