Figure 6.

[¹²⁵I]-CLINDE autoradiography images and quantitative analyses. [¹²⁵I]-CLINDE autoradiography images of the representative control and KASE (severe SE) rats and quantitative analysis of [¹²⁵I]-CLINDE specific binding (kBq/mg) in the control (N = 4) and KASE (N = 5) groups of dorsal hippocampal sections are shown. Data were pooled for medium (N = 2) and severe SE (N = 3) groups as qualitative inspection indicated that there was no difference in TSPO binding between the medium and severe groups. OX-42 + ve, OX-42 positive staining. Upward arrow indicates increase; plus sign, mild; double plus sign, moderate; and triple plus sign, intense OX-42 signals. Data are expressed as mean ± SEM; P < 0.05 (asterisk), P < 0.01 (double asterisk) and P < 0.001 (triple asterisk).