Table 1.
Differential gene expression between baseline COPD pBECs and healthy control pBECs
| SYMBOL | GENE NAME | FOLD CHANGE | P value |
|---|---|---|---|
|
Protease and Antiproteases |
|
|
|
| MMP10 |
Matrix metallopeptidase 10 |
2.94 |
0.0029 |
| PI3 |
Peptidase inhibitor 3 (Elafin) |
2.22 |
0.0287 |
| ADAM19 |
ADAM metallopeptidase domain 19 |
2.13 |
0.0090 |
|
Innate immunity |
|
|
|
| S100A8 |
S100 calcium binding protein A8 |
2.63 |
0.0189 |
| S100A9 |
S100 calcium binding protein A9 |
2.32 |
0.0143 |
|
Epithelial cell related processes |
|
|
|
| KRT6C |
Keratin 6C |
10.01 |
0.0002 |
| RHCG |
Rh family, C glycoprotein |
2.51 |
0.0033 |
| CNFN |
Cornifelin |
2.23 |
0.0213 |
| SPRR2E | Small proline-rich protein 2E | 2.15 | 0.0017 |