Table 1.
Participant population characteristics at study entry
|
Characteristic |
SAD |
BDI |
All |
|---|---|---|---|
| n = 64 | n = 175 | N = 239 | |
|
Demographics |
|
|
|
| Age, mean (range), years |
39.6 (20–66) |
42.6 (19–79) |
41.8 (18–79) |
| Gender, women,%; |
50.0%; |
61.1%; |
58.3%; |
|
Clinical status |
|
|
|
| Age at first symptoms of mental illness, median (range), years |
18 (5–43) |
17 (3–65) |
17.5 (3–65) |
| CGI-BP-S overall score, mean (SD) |
3.7 (1.2) |
3.9 (1.4) |
3.8 (1.3) |
| YMRS total score, median (range) |
4.5 (0–39) |
5.0 (0–45) |
5.0 (0–45) |
| HAMD21 total score, mean (SD) |
15.5 (8.4) |
12.7 (8.5) |
13.4 (8.6)* |
| At least 1 hospital admission; past 3 months,%; |
35.9%; |
32.0%; |
33.1%; |
|
Functional status |
|
|
|
| EQ-5D health state score, mean (SD) |
61.6 (22.7) |
68.2 (18.8) |
66.4 (20.1)* |
| Daily smoker,%; |
56.3%; |
49.1%; |
51.0%; |
| Daily alcohol consumption; past 3 months,%; |
4.7%; |
13.1%; |
10.9%; |
| Alcohol dependence; past 12 months,%; |
14.1%; |
18.3%; |
17.2%; |
| Unemployed,%; |
48.4%; |
22.3%; |
29.3%;* |
| Employed/studying/housework,%; |
43.8%; |
68.6%; |
61.9%;* |
| Have a partner,%; |
26.6%; |
46.9%; |
41.4%;* |
| Considered suicide in the past month,%; | 75.0%; | 58.9%; | 63.2%;* |
Abbreviations: BD = bipolar I disorder; CGI-BP-S = Clinical Global Impressions-Bipolar Version – Severity of Illness scale (range 1–7); EQ-5D = EuroQol instrument; HAMD21 = 21-item Hamilton Depression Rating scale; SAD = schizoaffective disorder; SD = standard deviation; YMRS = Young Mania Rating Scale. *Indicates statistical significance (p < 0.05) for comparison of BD and SAD participants. All p values are based on Fisher’s exact test except for HAMD21 and EQ-5D scores, which were tested using F-test analysis of variance.