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. 2004 Feb 6;101(7):1981–1986. doi: 10.1073/pnas.0307317101

Fig. 3.

Fig. 3.

Anaerobe expansion in RAG-2–/– mice is reversed by AID+/+ but not AID–/– BM transplantation. (A) Small intestinal microflora in biopsy samples (black bars) and intestinal content (gray bars) of RAG-2–/– mice identified by using bacterial 16S rRNA universal primers. Samples were from 10-week-old mice (n = 4). (B) Microflora identified by microbiological methods in the small intestinal contents of RAG-2–/– mice (gray bars), RAG-2–/– mice injected with BM from AID+/+ mice (white bars), or RAG-2–/– mice injected with BM from AID–/– mice (black bars). (C) Fluorescence-activated cell sorting profiles of LP and spleen stained for B220, IgM, IgA, and peanut agglutinin (PNA) from the RAG-2–/– mice transferred with BM from AID–/– or AID+/+ mice. Numbers indicate the lymphocyte percentages in the gates. Data showed in B and C are from the same animals and are representative profiles from two sets of mice.