Table 5.
Comparison of the literatures for radiotherapy in hepatocellular carcinoma patients with portal vein tumor thrombosis
| Reference | N | Techniques | Fraction size (Gy) | Total dose (Gy) | Response (%) | Median survival (months) |
|---|---|---|---|---|---|---|
| Toya [10] |
38 |
3D-CRT |
1.8–4 |
40 (range, 17.5–50.4) |
CR = 15.8 |
9.6 |
| |
|
|
|
|
PR = 28.9 |
|
| Kim [11] |
59 |
3D-CRT |
2–3 |
30–54 |
CR = 6.8 |
Responder: 10.7 |
| |
|
|
|
|
PR = 39.0 |
Non-responder: 5.3 |
| McIntosh [14] |
20 |
Helical Tomotherapy |
2.5 |
50 |
PR = 6.2 |
9.6 |
| |
|
|
|
|
SD = 87.5 |
|
| Choi [15] |
9 |
Cyberknife |
10–12 |
30–36 |
CR = 11.1 |
8 |
| |
|
|
|
|
PR = 33.3 |
|
| Current study |
35 |
Helical Tomotherapy |
4.5–6 |
50 (range, 45–60) |
CR = 14.3 |
12.9 |
| |
|
|
|
|
PR = 28.6 |
Responder 13.9 |
| Non-responder 6.9 |
Abbreviations: Gy, Gray; PVTT, Portal vein tumor thrombosis; 3D-CRT, 3 dimensional conformal radiotherapy; CR, Complete response; PR, partial response; SD, Stable disease.