Table 1.
Association of polymorphisms in XRCC1 and the risk of acute dermatitis
| |
Dermatitis |
|
|
|
|---|---|---|---|---|
| Genotype | Grade 1–2 | Grade 3 | OR (95% CI) | pvalue |
|
XRCC1 (194Arg/Trp) |
|
|
|
|
|
Arg/Arg (wild-type) |
41 |
14 |
1.00 (ref) |
|
|
Arg/Trp |
42 |
10 |
0.697 (0.278–1.75) |
0.440 |
|
Trp/Trp |
7 |
0 |
NC |
NC |
|
XRCC1 (399Arg/Gln) |
|
|
|
|
|
Arg/Arg (wild-type) |
53 |
10 |
1.00 (ref) |
|
|
Arg/Gln |
28 |
14 |
2.65 (1.04–6.73) |
0.037 |
| Gln/Gln | 9 | 0 | NC | NC |
Abbreviations: ref = reference; NC = not calculated; OR = Odds ratio; 95%CI = 95% confidence interval.