Table 3.
Association of clinical factors and the risk of acute skin and oral mucosa reactions
| |
Dermatitis |
|
Mucositis |
|
||
|---|---|---|---|---|---|---|
| Grade 1–2 | Grade 3 | pvalue | Grade 1–2 | Grade 3 | pvalue | |
| Age (year) | ||||||
| Mean±SD |
49.3±12.3 |
50.8±10.2 |
0.587 |
48.2±12.5 |
51.5±10.7 |
0.144 |
| Gender |
|
|
|
|
|
|
| Male |
61 |
17 |
0.775 |
48 |
30 |
0.246 |
| Female |
29 |
7 |
|
18 |
18 |
|
| Drinking |
|
|
|
|
|
|
| Yes |
8 |
1 |
0.737 |
4 |
5 |
0.617 |
| No |
82 |
23 |
|
62 |
43 |
|
| Smoking |
|
|
|
|
|
|
| Yes |
49 |
12 |
0.698 |
36 |
25 |
0.795 |
| No |
41 |
12 |
|
30 |
23 |
|
| Body mass index | ||||||
| ≤25 |
73 |
20 |
1.00 |
55 |
38 |
0.571 |
| >25 |
17 |
4 |
|
11 |
10 |
|
| T-staging | ||||||
| T1 |
8 |
1 |
0.418 |
5 |
4 |
0.474 |
| T2 |
27 |
5 |
|
22 |
10 |
|
| T3 |
29 |
7 |
|
18 |
18 |
|
| T4 |
26 |
11 |
|
21 |
16 |
|
| N-staging | ||||||
| N0 |
10 |
0 |
0.240 |
8 |
2 |
0.219 |
| N1 |
19 |
5 |
|
12 |
12 |
|
| N2 |
46 |
12 |
|
36 |
22 |
|
| N3 |
15 |
7 |
|
10 |
12 |
|
| Chemotherapy | ||||||
| Yes |
77 |
21 |
1.00 |
55 |
43 |
0.343 |
| No |
13 |
3 |
|
11 |
5 |
|
| Radiotherapy technique | ||||||
| 3D-CRT |
40 |
8 |
0.327 |
29 |
19 |
0.642 |
| IMRT |
50 |
16 |
|
37 |
29 |
|
| Irradiation Dose (Gy) | ||||||
| Mean±SD | 42.37±5.09 | 43.16±4.43 | 0.493 | 29.48±10.16 | 30.92±10.38 | 0.460 |
Abbreviations: IMRT = intensity-modulated radiotherapy; 3D-CRT = three-dimensional conformal radiation therapy, SD = Standard deviation. Gy=Gray.