Fig. 5.

WNK4 is a regulator of CFEX, but not pendrin. (a) Effect of WNK4 on ¹⁴C formate uptake mediated by CFEX. Oocytes were injected with water or cRNA encoding CFEX alone or in combination with WNK4; ¹⁴C formate uptake was measured as described in Methods. Results of a representative experiment are shown. (b) Effect of WNK4 on ¹⁴C formate uptake mediated by pendrin. Oocytes were injected with water or cRNA encoding pendrin alone or in combination with WNK4 as indicated; ¹⁴C formate uptake was measured as described in Methods. Results of a representative experiment are shown.