Table 1. Vaccines, recombinant HA proteins and antibodies used in this study.
Human Vaccine (subtype) | Donor strains |
Influenza A (H1N1) | Influenza A/California/7/2009 |
Influenza A (H3N2) | Influenza A/Perth/16/2009(H3N2)-like* |
Influenza B | Influenza B/Brisbane/60/2008 |
Recombinant HA | Donor strains |
A/H1 | Influenza A/New Caledonia/20/1999 |
A/H5 | Influenza A/Vietnam/1203/2004 |
A/H7 | Influenza A/Netherlands/219/03 |
B | Influenza B/Malaysia/2506/2004 |
Antibodies | Immunogen |
Sheep anti-H1 A/California/7/2009(H1N1) | Influenza A/California/7/2009 |
Sheep anti-H3 A/Perth/16/2009(H3N2)-like | Influenza A/Wisconsin/15/2009 |
Sheep anti-HB B/Brisbane/60/2008 | Influenza B/Brisbane/60/2008 |
Sheep anti-H1 A/New Caledonia/20/1999 (H1N1) | Influenza A/New Caledonia/20/1999 |
Sheep anti-H5 A/Vietnam/1203/2004 (H5N1) | Influenza A/Vietnam/1203/2004 |
Rabbit Uni-1 Abs (universal anti-HA antibody) | Influenza HA fusion peptide [37], [38], [39] |
Rabbit anti-H1 A/California/7/2009(H1N1) | Influenza A/California/7/2009 |
Rabbit anti-H3 A/Victoria/210/2009(H3N2) | Influenza A/Victoria/210/2009 |
Rabbit anti-HB B/Brisbane/60/2008 | Influenza B/Brisbane/60/2008 |
Monovalent vaccine strain was A/Victoria/210/2009 (H3N2) and trivalent vaccine strain was A/Wisconsin/15/2009 (H3N2).