Skip to main content
. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Hum Genet. 2012 Nov 9;132(3):285–292. doi: 10.1007/s00439-012-1249-0

Fig. 2.

Fig. 2

The 7 exons of GATA4 (Top). Filled squares with orange are coding exons of GATA4. Each * symbol represents a mutation in the coding exons from human genome mutation database. The c.C754T and c.G848A mutations are indicated in red, missense mutation c. G755C resulting in the Arginine to Proline at amino acid 252 is indicated in green; The protein of GATA4 (Middle). Two highly-conserved GATA-type zinc finger domains indicated as light blue. R252W indicated in red square. Amino acids alignment of a portion of GATA4 protein from different vertebrate species (Bottom). The Arginine at residue 252 is highlighted.