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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Exp Neurol. 2012 Dec 21;241:125–137. doi: 10.1016/j.expneurol.2012.12.010

Figure 5.

Figure 5

Anterograde transport of NT3-GFP to the olfactory bulb. (A) NT3-GFP is distributed in bulb glomeruli (gl) at 5 days after sensory neuron infection. (B) Higher magnification image of glomeruli showing the punctate nature of the NT3-GFP label. The section is immunostained with doublecortin antibody to show the overlying olfactory nerve layer (onl). (C) The distribution of NT3-GFP and axonal OMP-IR overlaps within individual glomeruli. (D) Ad-NT3-GFP infected OSNs project axons containing vesicular-like GFP (arrow) to bulb glomeruli. (E) In contrast, neurons infected with control Ad-GFP project axons in which the GFP signal is distributed uniformly (inset). Epl, external plexiform layer; mcl, mitral cell layer. Bar in F= 35μm in A, 23μm in B-C, 14μm in D, 30μm in E, 7μm in inset.