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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Neurobiol Aging. 2012 Dec 20;34(5):1416–1425. doi: 10.1016/j.neurobiolaging.2012.11.014

Fig. 5.

Fig. 5

Age-dependent accumulation of ADan/pGlu-ADan in ADanPP7 mice. Using AB77 (A–H) and AB76-2 (I–P), ADan/pGlu-ADan immunoreactivity was detected already at 2 months of age in frontal cortex (A,I) and hippocampus (E,M) of ADanPP7 mice showing a strong increase at 4 (B,F,J,N), 13 (C,G,K,O) and 20 months of age (D,H,L,P). Scale bar: 200 µm (A–P)