Table 2. Functional activation correlates of childhood maltreatment during fearful face vs. shape processing.
| Mask | Hemisphere | Anatomical Area | Volume(μl) | X | Y | Z | Voxelwise Stats: Mean (SD) | Extracted rho (sig) † | ΔR2(sig.) † | Group Diff.† | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| T | p | T, p | |||||||||
| ROI | R | Insula (a)(−) | 1728 | 35 | 18 | 6 | −2.76(0.58) | 0.018(0.016) | −0.521(0.002) | 0.175(0.008) | −3.239, 0.003 |
| ROI | R | Anterior Cingulate (d)(−) | 960 | 12 | 34 | 15 | −2.84(0.69) | 0.016(0.014) | .0.444(0.010) | 0.183(0.015) | −3.688,0.001 |
| WB | L/R | Anterior Cingulate/Medial Fronal Gyrus/Middle Frontal Gyrus (d)(−) |
38784 | 3 | 41 | 14 | −2.57(0.46) | 0.022(0.014) | −0.629(<0.001) | 0.329(<0.001) | −3.568, 0.001 |
Cluster coordinates are for cluster center of mass as defined by Talairach stereotactic space; Negative (−) signs following anatomical area indicate a negative relationship; Extracted rho is the spearman's correlation of extracted % signal change and Childhood Trauma Questionnaire total score; ΔR2 represents the change in full model R2 and significance from inclusion of CTQ total score in a post-hoc regression of extracted cluster % signal changes against other model factors; Group Diffi column represents the post-hoc t-test (High CM vs. Low CM) of extracted % signal changes based upon a median split of IPV-PTSD sample into low and high CM-exposure groups; Descriptors for anatomical areas do not reflect stereotactic distinctions, but are estimates based upon the relative location of activation on the group map; Statistics with a † indicate a circular estimate and therefore may be inflated estimates of the true population parameter; a=anterior; d=dorsal; L=left; R=right; ROI=region of interest; WB=whole-brain.