Table 1.
Average auditory brain stem responses (ABRs) measured for P3H1 null and wild type mice. Averaging is done over 16 ears for each genotype.
| Frequency | 4 kHz | 8kHz | 16kHz | 32kHz |
|---|---|---|---|---|
| Wild types (dB SPL) | 66.6± .3 | 63.0 ± 3.6 | 41.8 ± 6.7 | 43.9 ± 3.2 |
| P3H1 nulls (dB SPL) | 87.3 ± 9.0 | 77.7 ± 8.3 | 59.3 ± 17.5 | 70.6 ± 23.6a |
| Mean (null) – Mean (wt) (dB SPL) | 20.7 | 14.7 | 17.4 | 26.7 |
| Statistical values (two sample t-test) |
df = 26 t = 3.5 p = 0.0008 |
df = 26 t = 3.6 p = 0.0006 |
df = 26 t = 3.5 p = 0.0009 |
df = 22 t = 3.5 p = 0.0008 |
| Mean (null) – Mean (wt) used for t-test (dB SPL) | > 12 | > 6 | > 0 | > 4 |
a
two ears were found unresponsive at 32kHz up to 100dB and were not included in the statistics.