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Product and inhibitory complexes in the active site of HPP. Zinc ions are presented as orange spheres while the enzyme residues are shown in blue. (A) Inorganic phosphate and L-histidinol bound at the active site of HPP from L. lactis. Inorganic phosphate is shown in orange and l-histidinol is shown in light green. (B) l-histidinol-arsenate ester, a substrate mimic, bound at the active site of HPP from L.lactis. Arsenate is shown in brown while l-histidinol is shown in dark green.
