Table 2.
Correlation between Measures of Blood Glycemic Variabilitya
| Mean | SD | HbA1c | MAGE | CV | Hyper180 | Hyper150 | Hypo60 | Hypo72 | IQR | |
|---|---|---|---|---|---|---|---|---|---|---|
| Mean | — | |||||||||
| SD | 0.56 | — | ||||||||
| HbA1c | 0.39 | 0.46 | — | |||||||
| MAGE | –0.39 | –0.87 | –0.40 | — | ||||||
| CV | NS | 0.90 | 0.34 | 0.45 | — | |||||
| Hyper180 | 0.82 | 0.82 | 0.42 | 0.47 | 0.40 | — | ||||
| Hyper150 | 0.89 | 0.59 | 0.34 | 0.43 | 0.31 | 0.89 | — | |||
| Hypo60 | NS | NS | NS | NS | 0.43 | NS | NS | — | ||
| Hypo72 | –0.46 | NS | NS | NS | 0.44 | NS | NS | 0.66 | — | |
| IQR | 0.57 | 0.91 | 0.43 | 0.52 | 0.78 | 0.68 | 0.61 | NS | NS | — |
SD, standard deviation; CV, coefficient of variation; IQR, interquartile range.
Pearson’s linear correlation coefficient among common measures of GV26,38 and HbA1c. Glycemic variability measures were calculated from 86 patients (24 h of CGM, sampling each 5 min). Mean amplitude of glycemic excursions was calculated as average of positive adjacent peak greater than 1 SD. Coefficient of variation was calculated as SD/mean. HyperX and HypoX were calculated as fractions of the total time above/below a given threshold, e.g., Hyper150 was time (in percent) spent above 150 mg/dl. Interquartile range (IQR) is the difference between 75th and 25th percentiles from distribution of blood glucose values. Unpublished data.