Table 2.
Performance of Closed-Loop Controllers on the 10 Adult Subjects Compared with the Open-Loop Responsea
| Control type | IFB | Peak BG (mg/dl) | Nadir BG (mg/dl) | TBG>180 (h) | AUCBG>180 (g/h/dl) |
|---|---|---|---|---|---|
| Open-loop no bolus | 297 (29) | 110 (0) | 7.8 (1.4) | 119 (27) | |
| Open-loop optimal bolus | 209 (9) | 73 (1) | 1.3 (0.4) | 16 (5) | |
| PID | No | 284 (14) | 91 (3) | 5.7 (0.3) | 85 (7) |
| Yes | 279 (14) | 92 (3) | 5.5 (0.3) | 81 (6) | |
| PDBASAL | No | 262 (12)b | 91 (3) | 3.8 (0.4)b | 53 (5)b |
| Yes | 252 (11)c | 102 (3)c | 3.5 (0.4)c | 46 (6)c |
a
Values are mean (standard error). Two-way repeated-measures analysis of variance (p < .05) with post hoc comparisons corrected for multiple comparisons following the method of Šídák was used to compare PID versus PDBASAL with or without IFB. TBG>180, duration for which BG > 180 mg/dl; AUCBG>180, area under the curve when BG > 180 mg/dl
b
Indicates that PDBASAL significantly reduced the value of the tested feature when compared with PID
c
Indicates that PDBASAL significantly reduced the value of the tested feature when both controllers were coupled with IFB