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. 2012 Aug 6;44(4):519–530. doi: 10.1080/09291016.2012.704801

Table 2.

Clock gene expressions in the mouse heart.

Gene Treatment Site MESOR Amplitude Acrophase (h)
Bmal1 Sham Atrium 4.0 ± 0.1§* 5.4 ± 0.1§*# 23.2 ± 0.3
Ventricle 1.2 ± 0.1§*# 1.7 ± 0.1§*# 23.2 ± 0.2
SCNX Atrium 2.9 ± 0.3§ 1.5 ± 0.2§ N/A
Ventricle 0.7 ± 0.1§ 0.4 ± 0.1§ N/A
ANSB Atrium 3.8 ± 0.2§ 2.2 ± 0.3§ 22.5 ± 0.1
Ventricle 0.9 ± 0.1§ 0.4 ± 0.1§ 22.1 ± 0.4
Per2 Sham Atrium 2.8 ± 0.3 2.5 ± 0.1§*# 12.8 ± 0.4
Ventricle 0.6 ± 0.1 0.5 ± 0.1§*# 12.6 ± 0.3#
SCNX Atrium 2.0 ± 0.2 1.3 ± 0.2§ N/A
Ventricle 0.6 ± 0.1 0.3 ± 0.1§ N/A
ANSB Atrium 2.6 ± 0.4 0.9 ± 0.4§ 11.5 ± 1.2
Ventricle 0.7 ± 0.1 0.04 ± 0.01§ 7.2 ± 2.3
Dbp Sham Atrium 5.8 ± 0.3§*# 7.2 ± 0.6§*# 9.9 ± 0.2
Ventricle 1.9 ± 0.1§*# 2.2 ± 0.2§*# 9.9 ± 0.3#
SCNX Atrium 3.6 ± 0.4§ 2.1 ± 0.4§ N/A
Ventricle 1.0 ± 0.1§ 0.5 ± 0.1§γ N/A
ANSB Atrium 2.7 ± 0.2§ 2.4 ± 0.4§ 8.0 ± 0.4
Ventricle 1.3 ± 0.1§ 1.5 ± 0.1§ 6.6 ± 0.1

Note: Data are mean ± SEM for 3–6 mice per group. MESOR, midline estimating statistic of rhythm; Sham, sham-operated; SCNX, suprachiasmatic nucleus lesioned; ANSB, autonomic nervous system block; N/A, not applicable.

§

One-way ANOVA p < 0.05, Bonferroni/Dunn, p < 0.05.

*

Sham vs. lesion;

#

Sham vs. ANSB;

γ

Lesion vs. ANSB.