Table 2.
Predictors of stable tumor engraftment
| All histologies |
clear-cell RCC |
|||
|---|---|---|---|---|
| Engrafted/Total |
(p)
|
Engrafted/Total |
(p)
|
|
| RCC histology | 0.15 | |||
| clear cell | 11/65 | |||
| papillary | 3/14 | |||
| chromophobe | 0/4 | |||
| oncocytoma | 0/5 | |||
| unclassified | 2/3 | |||
| VHL mutation (germline or somatic) | 0.59 | |||
| Mutant | 8/42 | |||
| Wild type | 2/6 | |||
| Tumor implanted from metastases | 4/5 | 0.0028 | 3/4 | 0.014 |
| Sarcomatoid differentiation | 5/10 | 0.012 | 4/9 | 0.038 |
| Fuhrman nuclear grade | 0.0008 | 0.002 | ||
| 1 | 0/2 | 0/2 | ||
| 2 | 1/32 | 0/26 | ||
| 3 | 5/34 | 4/22 | ||
| 4 | 7/13 | 5/11 | ||
| Focality | 1.000 | 0.52 | ||
| unifocal | 11/74 | 7/57 | ||
| multifocal | 1/7 | 1/4 | ||
| Size (cm) | 0.58 | 0.30 | ||
| ≤4 | 4/27 | 3/19 | ||
| >4-7 | 3/28 | 1/19 | ||
| >7-10 | 5/21 | 4/16 | ||
| >10 | 4/18 | 3/11 | ||
| Pathologic tumor stage | 0.0014 | 0.0026 | ||
| T1 | 1/37 | 0/28 | ||
| T2 | 3/15 | 2/9 | ||
| T3 | 5/25 | 4/21 | ||
| T4 | 3/4 | 2/3 | ||
| Pathologic lymph node stage | 0.0077 | 0.016 | ||
| N0 | 1/21 | 0/17 | ||
| N1 | 4/7 | 2/3 | ||
| Metastasis at presentation | 6/10 | 0.0014 | 4/7 | 0.013 |