Table 1.
Patient demographics
| Demographics | Pittsburgh Patients | Pisa Patients | All patients |
|---|---|---|---|
| Number of Subjects | 105 | 67 | 172 |
| Number of Observations | 320 | 153 | 473 |
| Number of Observations for each subject | 3.048 | 2.2836 | 2.75 |
| CYP2C19 genotype | |||
| Rapid metabolizers (RM, *17/*17) | 4 | 1 | 5 |
| Extensive Metabolizers (EM, *17/*1,*1/*1) |
54 | 23 | 77 |
| Intermediate Metabolizers (IM, *1/*2, *1/*3, *17/*2, *17/*3) |
28 | 15 | 43 |
| Poor Metabolizers (PM, *2/*2, *3/*3, *2/*3) |
3 | 0 | 3 |
| Missing | 16 | 28 | 44 |
| Age, Mean Years ± SD (range) | 38.84 ± 12.05 (20.4-64.67) | 40.58 ± 11.20 (21-65) | 39.52 ± 11.73 (20.41 - 65) |
| Weight, mean kg ± SD (range) | 81.6 ± 20 ( 31.9 - 139.7) | 67.8 ± 15.2 (40-116) | 76.25 ± 19.45 ( 31.9-139.7) |
| BMI, mean lbs/in2 ± SD (range) | 28.20 ± 6.78 (15.55 - 48.26) | 24.94 ± 4.52 (16.63-37.41) | 26.93 ± 6.20 (15.55 - 48.26) |
| Sex, n (%) | |||
| Male | 47 (45) | 7 (10) | 54 (31) |
| Female | 58 (55) | 60 (90) | 118 (69) |
| Race, n (%) | |||
| White | 94 (89) | 67 (100) | 161 (93) |
| Black/African American | 8 (8) | 0 (0) | 8 (5) |
| Asian | 3 (3) | 0 (0) | 3 (2) |