Table 4.
Post-processed individual empirical Bayes estimates on clearance
| Population | Mean Clearance (L/Hr) |
Standard Deviation (L/Hr) |
P value |
|---|---|---|---|
| Genotype information | <0.005 | ||
| Rapid and Extensive (n=82) | 29.73 | 13.13 | |
| IM and PM (n=46) | 22.23 | 11.04 | |
| Missing (n=44) | 23.41 | 10.65 | |
| Age | <0.005 | ||
| < 30 years old (n=45) | 31.03 | 14.88 | |
| 30~50 years old (n=84) | 25.71 | 11.31 | |
| 50~65 years old (n=43) | 21.74 | 9.89 | |
| Clinical Trial Location | <0.001 | ||
| Pittsburgh patients (n=105) | 28.55 | 13.54 | |
| Pisa patients (n=67) | 22.28 | 9.32 |