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. Author manuscript; available in PMC: 2013 Feb 13.
Published in final edited form as: Annu Rev Pathol. 2011;6:121–145. doi: 10.1146/annurev-pathol-011110-130203

Figure 6.

Figure 6

Defects in osteoclast function in osteopetrosis. The sites of the four main genetic defects in osteoporosis—CAII (carbonic anhydrase), V-ATPase (proton pump), CLCN7 (chloride channel), and CTSK (cathespin K)—are highlighted in blue.