Appendix Table 1.

Adjusted^a Hazard Ratios and 95% Confidence Intervals for the Association Between Clinically Defined Cutpoints of Serum 25-Hydroxyvitamin D Concentration and Mortality Among Subjects Nested Within the General Population Trial of Linxian, China, 1986–2010

Circulating 25(OH)D, nmol/L	Total Deaths			Cancer Deaths			UGI Cancer Deaths			Cerebrovascular Deaths			Cardiovascular Deaths
	No. of Deaths	HR	95% CI	No. of Deaths	HR	95% CI	No. of Deaths	HR	95% CI	No. of Deaths	HR	95% CI	No. of Deaths	HR	95% CI
<25	274	1.00	Referent	75	1.00	Referent	62	1.00	Referent	95	1.00	Referent	68	1.00	Referent
25–37.4	175	1.08	0.89, 1.31	57	1.24	0.88, 1.76	47	1.25	0.85, 1.83	48	0.92	0.65, 1.30	53	1.31	0.91, 1.88
37.5– 49.9	130	0.96	0.78, 1.19	28	0.78	0.51, 1.21	24	0.81	0.51, 1.31	55	1.22	0.87, 1.70	32	0.93	0.61, 1.42
50–74.9	114	1.01	0.81, 1.27	35	1.10	0.73, 1.65	24	0.90	0.56, 1.45	40	0.97	0.67, 1.40	24	0.94	0.59, 1.50
75–99.9	57	1.00	0.75, 1.33	15	1.00	0.57, 1.75	11	0.89	0.47, 1.71	22	1.19	0.75, 1.91	13	0.89	0.49, 1.63
≥100	43	1.15	0.83, 1.59	7	0.77	0.35, 1.67	7	0.93	0.43, 2.05	19	1.60	0.97, 2.63	10	0.94	0.48, 1.84
P for trend		0.621			0.169			0.310			0.128			0.293

Abbreviations: 25(OH)D, 25-hydroxyvitamin D; CI, confidence interval; HR, hazard ratio; UGI, upper gastrointestinal.

^a Models were stratified on age and sex, with additional adjustment for separate continuous age variables for each stratum, as well as sex, hypertension, tobacco smoking, body mass index, and alcohol consumption.