Fig 3.

Histological sections of mouse Rag1^−/− colons (A; control, positive colitis) and BmAsnRS-treated colons (B). AsnRS-treated colons show resolution of cellular infiltration in the lamina propria submucosa even at high magnification. Inflammatory score: A = 3.67 ± 0.21 (n = 6 high power fields [hpf]) and B = 1.67 ± 0.33 (n = 12 high power fields [hpf]). P = 0.0010. Histological inflammation criteria include multiple indicators of transmural inflammation, epithelial hyperplasia, erosions, goblet cell mucus depletion, crypt abscesses, and ulceration (1).