Table 3.
Comparison of IgG responses to mycobacterial antigens according MAC-PD typea
| Antigen | Pathogen of MAC-PDb (n = 175) |
Radiographic findings of MAC-PDc (n = 89) |
||||||
|---|---|---|---|---|---|---|---|---|
|
M. avium (n = 84) |
M. intracellulare (n = 91) |
Nodular bronchiectasis (n = 69) |
Fibrocavitary (n = 20) |
|||||
| Median titer (IQR) | % sensitivity (no. of positive samples) | Median titer (IQR) | % sensitivity (no. of positive samples) | Median titer (IQR) | % sensitivity (no. of positive samples) | Median titer (IQR) | % sensitivity (no. of positive samples) | |
| MAV2054 | 0.459 (0.20–0.65)c | 51.2 (43) | 0.471 (0.31–0.74)c | 52.7 (48) | 0.389 (0.22–0.54)e | 40.6 (28) | 0.489 (0.28–0.68)f | 60.0 (12) |
| MAV5183 | 0.251 (0.15–0.44)c | 36.9 (31) | 0.337 (0.23–0.51)d | 50.5 (46) | 0.203 (0.12–0.39)e | 27.5 (19) | 0.379 (0.22–0.85)f | 65.0 (13) |
| HspX | 0.233 (0.14–0.37)c | 31.0 (26) | 0.266 (0.20–0.35)c | 39.6 (36) | 0.208 (0.14–0.30)e | 23.2 (16) | 0.216 (0.18–0.27)e | 15.0 (03) |
| 38-kDa | 0.100 (0.06–0.15)c | 26.2 (22) | 0.160 (0.11–0.30)d | 61.5 (56) | 0.107 (0.07–0.17)e | 34.8 (24) | 0.196 (0.11–0.45)f | 60.0 (12) |
a
Values indicated by superscript roman letters (“c” and “d” for comparisons between M. avium and M. intracellulare data and “e” and “f” for comparisons between nodular bronchiectasis and fibrocavitary data) represent significant differences according to a Mann-Whitney test that compared two unpaired groups (P < 0.05).
b
Classification by the disease-causing mycobacteria.
c
Classification by the characteristic radiologic finding.