Table 1.
Amino acid positiona | PUUV M segment amino acid |
DNA vaccine amino acid |
|||||
---|---|---|---|---|---|---|---|
DTK/Ufa-97b | K27c | P360d | Hallnas B1e | PUU-M(x22) | PUU-M(s1) | PUU-M(s2) | |
10 | Y | Y | C | Y | Y | Y | Y |
38 | V | I | I | I | I | I | I |
187 | Q | Q | Q | D | Q | Q | Q |
207 | H | H | H | H | Y | Y | H |
312 | A | A | A | V | A | A | A |
416 | L | S | L | L | L | L | L |
448 | M | M | M | M | T | T | M |
492 | W | W | W | W | R | R | W |
501 | F | L | F | F | F | F | F |
604 | T | T | T | R | T | T | T |
649 | L | L | L | H | L | L | L |
650 | E | E | E | H | E | E | E |
675 | G | G | G | R | G | G | G |
690 | P | P | P | Q | P | P | P |
972 | Q | Q | Q | Q | R | R | Q |
1077 | G | G | G | P | G | G | G |
1097 | S | S | S | S | L | L | S |
M gene segment open reading frame amino acid position.
DTK/Ufa-97, PUUV strain DTK/Ufa (GenBank accession no. BAF49040).
K27, PUUV strain K27 (GenBank accession no. P41265).
P360, PUUV strain P360 (GenBank accession no. P41266).
Hallnas B1, PUUV strain Hallnas B1 (GenBank accession no. P21400).
Amino acids shown in bold are differences with respect to the PUUM(s2) sequence.