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. 2013 Mar;87(5):2420–2429. doi: 10.1128/JVI.01769-12

Fig 7.

Fig 7

CNS expression of cytokines involved in B-cell survival and differentiation. C57BL/6 mice were inoculated intracerebrally with 1,000 PFU of SINV. (A) Relative quantitation values in the brain and spinal cord for mRNAs of IL-6, IL-10, IL-21, and IL-17a. Each point is the mean ± SEM of three mice. Relative levels were normalized to endogenous GAPDH mRNA expression. (B) The flow cytometry gating scheme for detecting IL-21R+ B cells within the CD19+ population. (C) The gated cell number of IL-21R+-expressing B cells in SINV- and PBS-inoculated brain. Each point is the mean ± SEM of one experiment.