Fig 1.

Immunologic detection of SAα2,3-gal- and SAα2,6-gal-linked receptors in cotton rat trachea (left panels) and alveoli (right panels). The brown color (developed from DAB) indicates the presence of SAα2,3-gal or SAα2,6-gal as indicated. The original magnification is ×400. Arrows emphasize the positively stained cells. Note that in cotton rat trachea the staining for SAα2,3-gal is located mainly in mucin-producing cells (arrowheads), whereas the staining for SAα2,6-gal is seen mainly in ciliated cells (arrows). In lung, there is low to nondetectable staining for SAα2,3-gal but a strong staining for SAα2,6-gal, associated with type II (arrows) and some type I (arrowheads) pneumocytes.