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. 2013 Feb;87(4):2081–2093. doi: 10.1128/JVI.02741-12

Table 1.

State variables and model parameters for the intracellular capsid-stealing modela

Notation Definition Unit Value Reference(s)
    State variables
G Concentration of full-length dimerized HIV genomic mRNAs 1/μl
GDIP Concentration of full-length dimerized DIP genomic mRNAs 1/μl
C Concentration of encapsidation-competent capsids in cytoplasm 1/μl
m DIP (integrated) provirus copy number (i.e., MOI) Dimensionless
    Model parameters
θ Rate of accumulation of encapsidation-competent HIV genomes in cytoplasm 1/μl/day graphic file with name zjv9990972410005.jpg
kpck Packaging constant μl/day
α Loss of genome rate 1/day
β Loss of capsid rate 1/day
η Capsid-to-genome accumulation ratio Dimensionless 1.2 to 5 10 and 72
P Expression asymmetry between DIP and HIV Dimensionless 8 to 10 13
a

See Fig. 2A and equations 1 to 3.