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The proliferation (as assessed by [3H]thymidine incorporation) of LPS-stimulated highly purified responder B cells is also profoundly suppressed by Ly6G+-depleted CD11b+-enriched splenocytes obtained from 5-w.p.i. LP-BM5 mice. This pattern of results is representative of one additional experiment in which stimulation was provided by α-CD40 and soluble IL-4.
