Table 1.
Demographic and Clinical Characteristics on 185 Older Subjects with Major Depression Followed for 6 Months after Remission.
Had a Relapse | Remained Relapse-free | |||||||
---|---|---|---|---|---|---|---|---|
(N=33) | (N=152) | |||||||
N | Perc (%) | N | Perc (%) | Chi-square | p | |||
Gender | 0.0004 | 0.98 | ||||||
Female | 21 | 63.64% | 97 | 63.82% | ||||
Entry Status at Last MDD Episode | 2.29 | 0.13 | ||||||
Inpatient | 14 | 42.42% | 44 | 28.95% | ||||
Outpatient | 19 | 57.58% | 108 | 71.05% | ||||
Mann-Whitney Wilcoxon | ||||||||
Mean | SD | Range | Mean | SD | Range | z | p | |
Age | 75.12 | 6.27 | 64–86 | 71.96 | 7 | 60–89 | 2.41 | 0.02 |
Education (years) | 13.18 | 3.88 | 5–21 | 14.17 | 3.09 | 7–21 | −1.62 | 0.1 |
Age at Onset | 59.34 | 16.65 | 30–83 | 56.45 | 18.27 | 14–87 | 0.81 | 0.42 |
Duration of Last Episode | 53.25 | 42.46 | 3–174 | 66.5 | 74.75 | 3–522 | −0.26 | 0.79 |
Number MDD Episodes | 2.45 | 1.41 | 1–6 | 2.05 | 1.24 | 1–7 | 1.6 | 0.11 |
Entry (Index Episode) | ||||||||
DRS Total1 | 133.74 | 7.11 | 116–144 | 136.47 | 7.23 | 111–144 | −2.07 | 0.0387 |
CIRS Total2 | 6.23 | 3.13 | 2–3 | 5.51 | 3.24 | 0–19 | 1.08 | 0.28 |
IADL3 | 24 | 3.73 | 15–27 | 25.56 | 2.32 | 15–27 | −1.66 | 0.1 |
At Onset of Remission4 | ||||||||
DRS Total1 | 130.54 | 12.93 | 100–143 | 137.34 | 6.8 | 103–144 | −1.88 | 0.0593 |
CIRS Total2 | 5.96 | 3.23 | 0–12 | 4.6 | 3.14 | 0–13 | 1.93 | 0.06 |
IADL3 | 25.2 | 3.29 | 17–27 | 25.77 | 2.28 | 15–27 | −0.12 | 0.91 |
Antidepressant (AD) Drug Treatment | ||||||||
Intensity5 | 2.42 | 1.47 | 0–4 | 2.17 | 1.61 | 0–4 | 0.57 | 0.57 |
Mattis Dementia Rating Scale;
Cumulative Illness Rating Scale-Geriatric Version;
Philadelphia Multilevel Assessment Instrument – IADL Subscale;
When remission was first identified
Composite Antidepressant Score (CAD) in last month before relapse or in the sixth month.