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. Author manuscript; available in PMC: 2013 Apr 15.
Published in final edited form as: Biochem J. 2012 Apr 15;443(2):339–353. doi: 10.1042/BJ20112017

Fig. 7. Representation of HPV16 E7 structure and binding partners.

Fig. 7

HPV E7 proteins are approximately 100 amino acids and contain a single zinc finger domain. Three conserved regions designated CR1, CR2 and CR3 are homologous to Adenovirus E1A and SV40 large T antigen and are essential for viral oncogenesis. Identified binding partners of the N- and C-terminal domains are indicated below. Adapted with permission from [118].