Table 2.
Estimated ratios of mean tumor platinum concentration
| Fold-increase in mean tumor Pt * | 95% CI | p value | |
|---|---|---|---|
| CBDCA 85 vs. CBDCA 12.4 mg/kg | 4.24 | (1.70, 11.04) | <0.01 |
| DDP vs. CBDCA 85 mg/kg | 0.78 | (0.27, 2.21) | 0.63 |
| DDP vs. CBDCA 12.4 mg/kg | 3.37 | (1.18, 9.58) | 0.02 |
Mean differences and their standard errors were calculated from log-transformed data using a random intercept model; values reported here are exponentiated model estimates and so estimate the ratio of the geometric means estimated in Table 2.