Table 1.
Baseline Characteristics
| No Transfer (n=3667) | Transferred (n=2075) | p-value | |
|---|---|---|---|
| Age, median (Q1, Q3), years | 61 (52, 71) | 61 (53, 70) | 0.906 |
| Female sex, n(%) | 841 (22.9) | 483 (23.3) | 0.767 |
| Clinical History, n(%) | |||
| Diabetes | 585 (16.0) | 328 (15.8) | 0.885 |
| Hypertension | 1809 (49.3) | 1030 (49.6) | 0.823 |
| Prior MI | 468 (12.8) | 226 (10.9) | 0.037 |
| Prior PCI | 395 (10.8) | 167 (8.0) | 0.001 |
| Prior CABG | 82 (2.2) | 46 (2.2) | 0.962 |
| Prior CHF | 132 (3.6) | 76 (3.7) | 0.902 |
| Prior AF | 152 (4.1) | 86 (4.1) | 0.999 |
| Prior Stroke | 142 (3.9) | 74 (3.6) | 0.558 |
| COPD | 174 (4.7) | 108 (5.2) | 0.439 |
| Current smoker | 1567 (42.8) | 910 (44.0) | 0.378 |
| Peripheral Vascular Disease | 156 (4.3) | 90 (4.3) | 0.881 |
| High Risk Inferior (ECG), n(%) | 1527 (41.6) | 818 (39.4) | 0.100 |
| Sum ST Segment Deviation, (Q1, Q3), mm | 13.0 (9.0, 18.5) | 13.0 (9.0, 18.5) | 0.428 |
| Heart rate, (Q1, Q3), bpm | 75 (64, 86) | 76 (65, 87) | 0.012 |
| Systolic blood pressure, (Q1, Q3), mmHg | 133 (117, 150) | 132 (118, 150) | 0.994 |
| Killip > I, n(%) | 390 (10.6) | 221 (10.7) | 0.981 |
| Creatinine, (Q1, Q3), μmol/L | 90.0 (79.6, 106.1) | 88.4 (78.0, 106.1) | 0.005 |
| Time Intervals | |||
| Symptom to Presentation, (Q1, Q3), min | 101 (60, 159) | 82 (46, 139) | <0.001 |
| Door to Balloon time, (Q1, Q3), min | 76 (55, 104) | 132 (107, 167) | <0.001 |
| Door to Balloon time <90 min, n (%) | 2417 (65.9) | 386 (18.6) | <0.001 |
| Door to Balloon time <120 min, n (%) | 3096 (84.4) | 889 (42.8) | <0.001 |
| D1D2, (Q1, Q3), min | — | 84 (61, 114) | — |
| DiDo non-PCI center, (Q1, Q3), min | — | 43 (26, 70) | — |
| Transportation Time, (Q1, Q3), min | — | 35 (24, 50) | — |
| PCI Center Arrival to Balloon Time Patients, (Q1, Q3), min | 76 (55, 104) | 45 (32, 61) | <0.001 |
| Symptom to Balloon time | 184 (139, 253) | 229 (179, 297) | <0.001 |
| Weekend Presentation, n (%) | 796 (21.7) | 469 (22.6) | 0.432 |
| Weekday Evening Presentation (6pm–6am), n (%) | 669 (18.2) | 394 (19.0) | 0.465 |
| Hospital Location, n(%) | <0.001 | ||
| North American | 1406 (38.3) | 680 (32.8) | |
| Australia/New Zealand | 1204 (32.8) | 557 (26.8) | |
| West Europe | 624 (17.0) | 713 (34.4) | |
| East Europe | 433 (11.8) | 125 (6.0) | |
Abbreviations: AF, atrial fibrillation; bpm, beats per minute; CABG, coronary artery bypass grafting; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; D1D2, time from arrival at first hospital to second hospital; DiDo, Door in to door out time at non-PCI centers; ECG, electrocardiogram; min, minutes; mm, millimeters; mmHg, millimeters mercury; n, number; MI, myocardial infarction; Q1, first quartile; Q3, third quartile; PCI, percutaneous coronary intervention.