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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Future Neurol. 2012 Sep;7(5):557–571. doi: 10.2217/fnl.12.47

Figure 3. Schematic summary of the effects of acetylcholine on synaptic transmission and plasticity.

Figure 3

Increased levels of ACh suppress intrinsic connections, boost transmission rates of extrinsic projections and reduce the threshold for the induction of LTP. Reduced levels of ACh boost transmission rates of intrinsic projections and increase the threshold for the induction of LTP, increasing the probability that LTD is induced.

ACh: Acetylcholine; LTD: Long-term depression; LTP: Long-term potentiation.

Adapted from [8] with permission from Elsevier.